Clinical Pathways
Evidence for cancer treatment is constantly evolving. This can result in lag times for system-wide implementation and variability in treatments for Veterans. Clinical Pathways are a decision support tool that bridge this gap by translating published evidence into standardized treatment process maps to help guide treatment decisions.
Clinical Pathways standardize evidence-based practices to ensure high quality, cost-effective care for Veterans at each point in their care plan. Clinical Pathways are different from treatment guidelines, as Clinical Pathways recommend a standard treatment based on efficacy, toxicity, and cost. Guidelines, on the other hand, offer treatment options without always prioritizing specific recommendations. Clinical Pathways are developed by an interdisciplinary subject matter expert group and approved by national program offices including medical oncology, radiation oncology, surgery, pathology, and pharmacy.
Brain and Central Nervous System (CNS) Cancer Clinical Pathways
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Glioblastoma
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IDH Mutant Astrocytoma
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Meningioma
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Oligodendroglioma
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Primary CNS Lymphoma (CNS-DLBCL)
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Vestibular Schwannoma
Breast Cancer Clinical Pathways
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Breast Cancer(in CPRS)
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Breast Cancer Risk Reduction
Gastrointestinal (GI) Cancer Clinical Pathways
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Ampullary Cancer
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Anal Cancer
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Biliary Tract Cancer
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Colon Cancer(in CPRS)
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Esophageal Cancer(in CPRS)
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Gastric (Stomach) Cancer
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GI Neuroendocrine Tumors (NETs)
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Hepatocellular (Liver) Carcinoma
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Pancreatic Cancer
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Rectal Cancer
Genitourinary (Genital and Urinary) Cancer Clinical Pathways
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Bladder Cancer
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Kidney (Renal) Cancer(in CPRS)
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Prostate Cancer(in CPRS)
Gynecologic Cancer Clinical Pathways
Head and Neck Cancer Clinical Pathways
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Head and Neck Cancer(in CPRS)
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Salivary Gland Cancer
Hematologic (Blood-Related) Malignancies Clinical Pathways
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Acute Myeloid Leukemia
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Acute Promyelocytic Leukemia
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Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
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Chronic Myeloid Leukemia
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Classic Hodgkin Lymphoma (Hodgkin Disease)
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Diffuse Large B-Cell Lymphoma
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Essential Thrombocytosis
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Follicular Lymphoma
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Hairy Cell Leukemia
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Mantle Cell Lymphoma
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Marginal Zone Lymphoma
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Myelodysplastic Syndromes
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Peripheral T-Cell Lymphoma
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Plasma Cell Disorders
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Polycythemia Vera
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Primary and Secondary Myelofibrosis
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Primary Mediastinal B-Cell Lymphoma
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Waldenstrom Macroglobulinemia and Lymphoplasmacytic Lymphoma
Lung Cancer and Mesothelioma Clinical Pathways
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Lung Cancer(in CPRS)
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Lung Carcinoids
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Mesothelioma
Molecular Testing Provisional Recommendations
Sarcoma Clinical Pathways
Skin Cancer Clinical Pathways
Clinical Pathways are reviewed at least quarterly by subject matter experts and updated if changes are made. Previous versions are archived and available to internal users within the VA network on the Clinical Pathways SharePoint.
We appreciate hearing how you use these pathways or suggestions for future refinement. Click on the Pathways Feedback button below if you wish to provide us with feedback on our Clinical Pathways.